Wednesday, June 9, 2010

Prediction of CpG-island function: CpG clustering vs. sliding-window methods

Hackenberg et al. show that their clustering method, CpGcluster, is better at detecting short, often differentially methylated CpG islands
than sliding-window methods.
"The major difference in the prediction was found for short islands (CpG islets), often exclusively predicted by CpGcluster."

http://www.biomedcentral.com/1471-2164/11/327/abstract

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