Saturday, March 27, 2010

The next medium, whatever it is-

"The next medium, whatever it is - it may be the extension of consciousness - will include television as its content, not as its environment, and will transform television into an art form.  A computer as a research and communication instrument could enhance retrieval, obsolesce mass library organization, retrieve the individual's encyclopedic function and flip it into a private line to speedily tailored data of a saleable kind."
-Marshall McLuhan

Posted via email from the nocx files

"The user is the content."

- Marshall McLuhan

Posted via email from the nocx files

"We look at the present through a rearview mirror. We march backwards into the future."

-Marshall McLuhan

Posted via email from the nocx files

Sunday, March 21, 2010

Do rare variants create "synthetic" associations in GWAS?

Rare Variants Create Synthetic Genome-Wide Associations

The hypothesis is that rare variants could have “synthetic associations” by happening, stochastically, more often in association with one allele at the common site compared to the other allele at that site.  The authors use smulations are used to show the conditions underneath which synthetic associations might occur.
"Now it is demonstrated in a simulation study that even those signals that have been detected for common variants could, in principle, come from the effect of rare ones. This has important implications for our understanding of the genetic architecture of human disease and in the design of future studies to detect causal genetic variants."

Posted via email from the nocx files

PLoS Genetics David Clayton on GWAS

Prediction and Interaction in Complex Disease Genetics: Experience in Type 1 Diabetes

Posted via email from the nocx files

Hudson River Sunset - photo

Apple Store, Meat Packing District NYC. (pic)

Saturday, March 6, 2010

Liked JAMIA: Quantifying clinical narrative redundancy in an electronic record

Records examined from 100 randomly selected patient admissions.
Documents aligned using a modified version of an established DNA sequence
alignment algorithm (Levenshtein edit distance algorithm). High levels of 
redundancy were observed with successive documents of the 
same type, and across document types.

Posted via email from the nocx files

IJMI - Attitudes and behaviors related to the introduction of electronic health records among Austrian and German citizens

Most interviewed collect paper based data at home. Few use PHRs.
Most support exchange of information between providers. 
Many have concerns about security.

Posted via email from the nocx files

Bike art. Hugh Black. #TRUENORTH 29er

Bike-- Masi Soulville SS

Friday, March 5, 2010

mnmlist on simple productivity

why Kindle will go the way of the compact disc

"Doctorow's Law," : "Any time someone puts a lock on something you own, against your wishes, and doesn't give you the key, it's not being done to your benefit."

Posted via email from the nocx files


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