Nature Medicine: Negative regulator of MAP kinase involved in depression. MKP-1.

http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.2219.html

MAP kinase phosphatase 1 (MKP-1) /DUSP1.

Another study that points to this pathway, from the lab of Ron Duman.

Expression study in human post-mortem MDD brain and rat and mouse models. 

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