'Genomic Regions Enrichment of Annotations Tool'
Mclean et al.
Nat Biotechnol 28:495–501 2010
The software completes an analysis showing which genes a transcription factor is likely to influence, and the relevant molecular pathways, across the genome. It incorporates proximal and distal binding and controls for false positives using a binomial test.
http://www.nature.com/nbt/journal/v28/n5/abs/nbt.1630.html 
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