Cheung et al. PLoS Biology 2010
Polymorphic cis- and trans-regulation of human gene expression
"The majority of the regulators act in trans to the target (regulated) genes. Most of these trans-regulators were not known to play a role in gene expression regulation. The identification of these regulators enabled the characterization of polymorphic regulation of human gene expression at a resolution that was unattainable in the past."
http://www.ncbi.nlm.nih.gov/pubmed/20856902
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