Thursday, May 6, 2010

Analysis of a polymorphic microRNA target site in the purinergic receptor P2RX7 gene

Science: A Draft Sequence of the Neandertal Genome

"a draft sequence of the Neandertal genome composed of more than 4 billion nucleotides from three individuals. Comparisons of the Neandertal genome to the genomes of five present-day humans from different parts of the world"

http://www.sciencemag.org/cgi/content/full/328/5979/710

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PNAS: Epigenetic and immune function profiles associated with posttraumatic stress disorder

n=23 cases 
77 controls
"immune system functions are significantly overrepresented among the annotations associated with genes uniquely unmethylated among those with PTSD."

Could this be a result of HPA axis dysregulation?

http://www.pnas.org/content/early/2010/04/19/0910794107

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The case for cloud computing in genome informatics

"impending collapse of the genome informatics ecosystem"

http://genomebiology.com/2010/11/5/207

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Sunday, May 2, 2010

BMC Medical Genetics - Characterizing the founder structure of the Old Order Amish. via @BioMedCentral.

128 founders (78 females and 50 males) accounted for over 95% of the mean relative founder contribution among living Old Order Amish descendants, according to analyses with PedHunter 2.0.

Posted via email from the nocx files

McLuhan on the objectives of new media.

"The objectives of new media have tended, fatally, to be set in terms of the parameters and frames of the older media."

-Marshall McLuhan

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@huffingtonpost: Electronic Medical Record Shift: Signs Of Harm Emerge As Doctors Move From Paper

Machines don't make things perfect. Some of the known issues with
computers in health care are discussed, including electronic ordering.

http://www.huffingtonpost.com/2010/04/20/electronic-medical-record_n_545441.html

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